Studies on Fish Extracts (Part 1)

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: genotoxicity.

Public interest in green tea has grown recently due to the potential health benefits from its consumption. Epigallocatechin gallate (EGCG), a principal polyphenolic component of green tea, is considered key to these healthful qualities. Although numerous studies have evaluated the anti-cancer effects of green tea and EGCG, few have examined the safety of EGCG consumption. The genotoxic potentia...

STUDIES ON HYDRALAZINES - PART-1x1 PREPARATION AND ANTIMICROBIAL ACTIVITY OF 1 - (PHTHALAZIN- 1 '-YLAMINO)- 3-CHLORO-4-ARYL- 4H-(OR 4-METHYL)-2-AZETIDINONE

1- (Phthalazin-l'-yl-amino)-3-chloro-4-aryl-4H-(4o-rm ethyl)-2-azetidinones (3) were prepared by cycloaddition of-methyl substituted benzal hydrazinophthalazine (2) with chloro acetylchloride. The hydrazone (2) was synthesised by the condensation of 1- hydrazinophthalazine (1) with substituted aromatic aldehydes, ketones 7 acetophenones. 1- Hydrazinophthalazine was prepared from the phthal...

Further Studies on Effects of Tissue Extracts on Staphylococcus Aureus

1. The ability of alcoholic-precipitated extracts of beef tissue-brain, spleen, heart, and kidney-to stimulate the growth of Staphylococcus aureus, in vitro, and to convert the yellow S form to a white R variant with altered biochemical characteristics conforming to those of an avirulent organism, has been confirmed. 2. The avirulence of the white R variant has been established by tests in vivo...

Studies on Quercus lusitanica Extracts on DENV-2 Replication

This study aimed to search for compounds with potential inhibitory activities towards DENV-2 replication. In vitro inhibitory activities of plant extracts towards DENV-2 replication were studied and the proteomics profile of cells infected with dengue virus, followed by treatment with plant extracts, were mapped out. Methanol crude and fractionated extracts of Quercus lusitanica were tested. Th...

Studies on hexokinase. 1. The hexokinase activity of rat-brain extracts.